Detection of Antibacterial Activity of Clove Extract on Pseudomonas Aeruginosa Isolated from Patients Visiting Tertiary Care Hospital

Abstract

Pseudomonas aeruginosa has become one of the major threats to public health as it causes serious infections like Hospital Acquired Infection and the condition becomes worse if it is caused by drug-resistant strain. To overcome this resistance natural products, have a great therapeutic property. Thus, this study was aimed to determine antibacterial activity of clove extract such as Infusion, Decoction and Clove oil against Pseudomonas aeruginosa isolated from clinical specimen of patients visiting tertiary care hospital. Total 250 number of P. aeruginosa were isolated from clinical samples such as Blood, Sputum, Urine, ET secretion, Pus, etc. Patients of age group from 18-80 were included in this study with 154 MDR isolates. Maximum number of P. aeruginosa isolates were found in ICU patients. Clove oil was susceptible to all 250 isolates of P. aeruginosa with mean zone of 23.59 ± 4.72 Standard deviation. These findings suggest the potential of clove oil as an adjuvant therapy along with antimicrobial agent against infection caused by Pseudomonas aeruginosa.