Incorporation of Striga Orobanchioides Extract in Denture Adhesives & Its Antifungal Effect on Acrylic Resins: An Invitro Study

Abstract

Introduction: Denture stomatitis is a common condition affecting removable denture wearers, primarily caused by Candida albicans colonization and biofilm formation on the denture base. The prolonged use of denture adhesives, while beneficial for retention and stability, may alter oral microflora and increase susceptibility to fungal infections.

Aim: This study evaluates the antifungal efficacy of Striga orobanchioides extract-based denture adhesive in preventing C. albicans adhesion and biofilm formation on acrylic denture bases.

Material and methodology: Ethanolic extracts of Striga orobanchioides were incorporated into a denture adhesive formulation. The antifungal activity was assessed using microbiological assays to determine the inhibition of C. albicans growth and biofilm formation. The color stability was also evaluated to ensure clinical applicability.

Results: Findings suggest that Striga orobanchioides extract exhibits significant antifungal activity against C. albicans, reducing its adhesion to the denture surface.

Conclusion: The incorporation of Striga orobanchioides extract into denture adhesives demonstrates promising antifungal potential, offering a novel approach to managing denture stomatitis. Further clinical studies are required to confirm its long-term efficacy and safety for routine use.