Qualitative and Quantities Estimation Phytochemical of Saccopetalum Tomentosum Leaf Extracts

Abstract

Natural products from plants continue to serve as promising sources of biologically active compounds for drug development. Saccopetalum tomentosum (Annonaceae), a deciduous tree widely found in India and Southeast Asia, is traditionally used for its antibacterial, anticancer, anthelmintic, and antiparasitic properties. This study aimed to evaluate the pharmacognostical, phytochemical, and in vitro antioxidant activities of S. tomentosum leaves collected from the Bhopal region of Madhya Pradesh. Standard methods were used for pharmacognostical and phytochemical analysis. Quantitative estimation of total phenolics and flavonoids was performed using Folin–Ciocalteu and aluminum chloride methods, respectively. Ethanolic extracts showed significant phenolic (323.667 mg/100 mg) and flavonoid (448.333 mg/100 mg) contents. Antioxidant activity of chloroform, ethyl acetate, and ethanolic extracts was assessed using DPPH, SOS, and reducing power assays, revealing concentration-dependent activity. The presence of diverse phytochemicals such as alkaloids, flavonoids, glycosides, and triterpenoids supports the plant’s potential as a therapeutic agent in modern and traditional medicine. The high TPC and TFC values in Saccopetalum tomentosum leaf extracts suggest a strong presence of bioactive compounds. These phytochemicals are known for their health benefits, including antioxidant and antidiabetic effects, supporting the plant’s traditional use. The results validate its potential for further pharmacological and therapeutic investigations.