Comparative Evaluation of DEFLAZACORT with or without Twin Mix Local Anesthesia in Impacted Third Molar Surgeries-A Randomized Clinical Trial

Abstract

Aim & Background: To assess and compare the effect of Deflazacort with or without twin mix local anesthesia in surgically removed impacted mandibular third molars following surgery problems such as pain, swelling, and opening of the mouth.  In a usual dental practice, Removal of the third molar is among the most often executed surgeries. The third set of molars is the last group of teeth at the back of the mouth. Surgical intervention may be necessary in complex situations, involving bone removal and gum tissue incision. Patients may have discomfort, edema, and pain following surgery.

Materials and Methods: On 30 patients, a randomised control study was carried out. Patients had their completely impacted lower third molars surgically removed. There were 2 groups: Group A, which got Deflazacort without twin mix local anesthesia following tooth was extracted, and Group B, which got Deflazacort solution. The mouth-opening scores were compared using the Chi-square test, whereas the continuous data for pain and edema were compared Within the two groups using the Mann-Whitney U test.

Results: Ater 1 week of treatment, no significant change in pain was noted in Group A, but significantly lower in pain score in Group B compared to Group A after 1-week and 1-month post treatment. Similarly, after 1 week and 1 month, it was found that participants under the Group B had less swelling when compared to participants in Group A but after 1 month it was not statistically significant. But for mouth opening, it was found that after one week, one month, and three months, there was discernible statistical disparity between the mean mouth-opening among participants between the Group A and Group B.

Conclusion: When compared to Group A, the use of Deflazacort with twin mix of local anesthesia significantly reduced postoperative problems such pain, swelling, and opening of the mouth following surgical excision of the lower third molar.

Clinical significance: This study is clinically significant in proving further that Deflazacort with twin mix of local anesthesia is more efficient than Deflazacort without twin mix of local anesthesia in reducing postoperative complications of pain, swelling, and limited mouth opening associated with surgical removal of impacted mandibular third molars.

Categories: Dentistry, Dermatology, Therapeutics, Esthetics