Comparative Evaluation of Presurgical and Post Surgical Nutritional Status in Patients with Oral Squamous Cell Carcinoma

Abstract

Background: The most frequent malignant epithelial neoplasm impacting the oral cavity is oral squamous cell carcinoma. Although OSCC can occur in a variety of oral cavity anatomical features, it typically manifests on the lower lip, floor of the mouth, and lateral edge of the tongue. A degree of nutritional status variations and a deterioration in quality of life (QoL) are common among individuals with OSCC.

Aim: The study was conducted to compare and evaluate the nutritional status in patients with OSCC before and after the surgery.

Methods: 30 patients aged between 25-75 years were underwent OSCC surgery in the department. The patients were divided into two groups randomly i.e., Group A: Presurgical status (n=25) and Group B: Post surgical status (n=25). The patient’s weight, BMI, serum albumin and quality of life were measured before the surgery and after 30 days of surgery. The obtained data were compared between the groups to compare the nutritional status of the patients.

Results: The comparative evaluation of presurgical and post-surgical nutritional status in patients with oral squamous cell carcinoma was studied in 30 patients with OSCC. There was a decline in BMI, weight and serum albumin level and quality of life post-surgery. The Fluid Intake increase before the surgery but there was a decline in the fluid output post-surgery.

Conclusion: The effects of OSCC on a patient's nutritional status and quality of life are emphasized in the present study, which also underscores the necessity of further studies to examine certain interventions that may support long-term improvements in QoL and nutritional status. It highlights a strong emphasis on providing these patients with individualized, comprehensive care.

Clinical Significance: The study highlights nutritional risk among the patients with OSCC at both presurgical and post surgically.