Evaluation of Wound-Healing Activity of Eupatorium Adenophorum Spreng Leaf Extract in Adult Wistar Rats

Abstract

Use of plant extracts in the treatment of several ailments is a science known to the mankind since time immemorial. Yet, its popularity is limited owing to the lack of recorded experimental evidence to determine their potential health benefits. Medicinal plants play indispensable roles to treat various ailments. Eupatorium adenophorum Spreng belonging to family Asteraceae used traditional as blood coagulation in different kinds of haemorrhage condition and the leaves of this plant are used in Ayurveda and other folk medicines for the treatment of cut and wounds.

Objectives: Evaluation of wound healing activity of Eupatorium adenophorum Spreng leaf extract in adult albino rats.

Materials and Methods: Dried alcoholic and aqueous extracts of the leaves of E. adenophorum Spreng dissolved in normal saline with the help of tween-80,&The blood coagulation activity was determined by tail bleeding method and the alcoholic extract shows more significant when compared with aqueous extract and control group.

Results: The extract of E. adenophorum Spreng exhibit good coagulation activity, pharmacological studies of the E. adenophorum Spreng extract shows that the alcoholic extract is more potent than aqueous extracts.