Reproductive Outcome 0f IVF in Asherman Syndrome Post Uterine Myomectomy.

Abstract

Background: Asherman syndrome, characterized by intrauterine adhesions, often results from uterine surgeries like myomectomy, leading to menstrual irregularity recurrant pregnancy loss and impaired fertility. Effective treatment including hysteroscopic adhesiolysis and assisted reproductive techniques, such as IVF, are essential for restoring menstrual cycle and fertility in affected women.

Objective: To evaluate in vitro fertilization (IVF) pregnancy outcomes in women who underwent treatment for Asherman syndrome (AS) following uterine myomectomy.

Methods: This observational study included 50 women who had ASHERMAN SYNDROME and a history of uterine myomectomy. Data was collected on demographics, IVF cycles, pregnancy rates, clinical pregnancy rates, live birth rates, and miscarriage rates. Statistical analysis was conducted using chi-square tests and Kaplan-Meier survival curves.

Results: The pregnancy rate was 60%, clinical pregnancy rate 50%, live birth rate 40%, and miscarriage rate 10%. Younger women (<35) had significantly better outcomes than older women. Women with moderate AS had higher IVF success rates than those with severe AS.

Conclusion: IVF remains a viable option for women with Asherman syndrome following uterine myomectomy, with success rates influenced by Age and AS severity. The study underscores the need for personalized treatment plans and the importance of early intervention in improving IVF outcomes for this patient group.