Incidence of Blood Glucose Level Abnormality During and after Cardiac Surgery Under Cardiopulmonary Bypass in Non-Diabetic Patient: A Prospective Observational Study

Abstract

Introduction: Glycaemic control in postoperative cardiac patients is necessary to improve outcomes in wound infection and overall mortality. In recent years, clinical trials evaluating blood glucose control in critically ill patients advocated for intense blood glucose management and found a significant reduction in morbidity and mortality.

Aims: To evaluate the incidence of blood glucose abnormality during and after cardiac surgery under cardiopulmonary bypass in non-diabetic patient. To evaluate any association of blood glucose abnormality with the arterial blood gas parameters (pH & HCO3,base exchange,)  during  prebypass/ onset of  bypass/mid bypass/ at the weaning from CPB/ at the time of ITU stay up to 48 hours post-operative (on entering ITU and at 6 hours, 12 hours, 24 hours, 36 hours & 48 hours) along with various inotropic drugs ,IV fluid, and insulin. To evaluate any association of blood glucose abnormality with the duration of CPB time.

Materials and Methods: The present study was a prospective observational study. This Study was conducted from Ten months (September 2017 - June 2018) at Dept. of CTVS, R.G.KAR Medical College And Hospital.

Result: Our study, use for the distribution of patient according to the operation undergone. Though In format 3 we distribute the patient In percentage not in number. It is seen that the valve replacement surgery (MVR, DVR, AVR) contributed the highest number of surgery [(27) 54%] in our department then other surgery, followed by CABG, ASD CLOSURE, VAD CLOSURE.

Conclusion: Blood glucose abnormalities, particularly hyperglycemia, are prevalent during and after cardiac surgery in non-diabetic patients undergoing CPB. These findings highlight the need for vigilant monitoring and management of blood glucose levels in this population to minimize postoperative complications.