“Evaluation of Quality Standards of Poly-Herbal Ayurvedic Compound (Kalingadi Churna) and Its Anti-Oxidant Activity”

Abstract

Introduction: The science of Ayurveda withholds innumerable formulations that are single drug, poly herbal and Herbo-mineral compounds. Only a few of these have been researched upon and are explored fully to their potential. One such formulation is Kalingadi churna which is said to have its effect in the management of Grahani roga, which can nearly be understood in terms of IBS. It is composed of the drugs Kalinga (Holarrhena antydysentrica), Ativisha (Aconitum heterophyllum), Hingu (Ferula narthex), Vacha (Acorus calamus), Haritaki (Terminalia chebula) and Saindhava lavana (Unaqua sodium chloride).

Material and Methods: The current study involved the preparation of a polyherbal Churna and the assessment of its constituents for macroscopic characters, physicochemical parameters, thin layer chromatography (TLC), and also conducting in vitro antioxidant activity. The antioxidant activity was examined using in vitro antioxidant models through DPPH free radical scavenging, Iron Chelating activity, and nitric oxide scavenging activity.

Result and Discussion: Based on the findings of this study, the formulation demonstrated a notable antioxidant capacity, which may be attributed to the presence of certain phytochemicals in the formulation. It also indicated that the polyherbal churna can serve as a readily available source of natural antioxidants and thereby helping in understanding its probable mode of action and thus making it a potential candidate for usage as a drug in various ailments of the gastrointestinal tract.