Serum VIT D Level and Adults Libyans Patients with Acne Vulgaris

Abstract

Back ground: Acne vulgaris  is a common  inflammatory skin disease and complex skin disorder that distresses many patients because of its chronicity. Vitamin D plays an important role in the immune system, and Vitamin D deficiency plays a role in many inflammatory skin diseases. It may play a role in pathogenesis of acne vulgaris .

Objectives: The aim of this study was to evaluate the serum 25 hydoxy vitamin D levels among patients with acne vulgaris  .

Method: All patients were subjected to detailed history taking and examination to detect extent and severity of acne vulgaris. Adolescents between the ages of 10 and 19 years, of either sex, with acne were clinically examined, and the severity of acne was evaluated using the Global Acne Grading System (GAGS) score.. Blood samples were taken from all participants to assess serum 25 OH D level were measured using a LIASON chemiluminescent Immunoassay. This cross-sectional study was conducted during the period April 2017 to April 2018 .

Result show that the mean ±SD vitamin D level of controls was higher (31.47± 66.19 ng/mL) compared to vitamin D level of diseased cases with a mean value of 19.52±12.38ng/mL). This difference was not significant, P > 0.05 . The study included 24males and 68 females . The mean age of patients were  Mean ± SD = 25.5± 8.5, Rang = 11- 50 years, Mode = 18, Median = 24. The mean of vitamin D level for control was more than the acne case, with highly statistical significant (p = 0.003). The  study showed that  had no a statistical difference between the acne severity and vitamin levels.