Advancement in Insulin Delivery Over the Period

Abstract

Insulin is a peptide hormone that regulates blood glucose in the body and is secreted from the β-cells of the pancreas, an organ situated behind the stomach, and is the primary source of insulin in the body. The year 2021 has completed 100 years in the discovery of insulin. The discovery of insulin proved to be a lifesaving phenomenon for people suffering from diabetes. Diabetes is a condition that may occur in two states: when the pancreas is not able to produce enough insulin or when the body is not able to use it. Delivery of insulin in the body was quite a typical task earlier because it cannot be directly administered orally like any other medicament. Therefore, various delivery devices are developed and chosen for the successful delivery of insulin in the body, the most promising devices are insulin syringes, jet injectors, pumps, and pens. In addition to this, a DIY-APS (Do-It-Yourself Artificial Pancreas) represents a significant milestone in diabetes treatment. This review centers on the progress and transformation of insulin delivery devices throughout history up to the present day.