Evaluation of Wound Healing and Burn Healing Activity of Ethanolic Fruit Extract of Nyctanthes Arbor-Tristis

Abstract

To study the wound healing potential of Nytanthes Arbor-tristis, the ethanolic fruit extract was used for evaluation of excision and burn in Wistar albino rats. Powdered crude material was extracted with 95% ethanol in soxhlet apparatus. Ointment containing 5% w/w ethanolic fruit extract of NAT was applied once daily to test groups of excision and burn wounds groups. The percentage of wound contraction and degree of healing were assessed at day 4, 8, 12 and 16, till complete closure of wounds. The extract ointment treated test group of excision and burn wound groups significantly increased wound healing and decreased epithelization time as compared to standard and control groups. Hence, 5%w/w fruit extract of NAT could be used for treatment of both types of wounds.