A Study on Clinical Profile of Cerebral Venous Thrombosis

Abstract

Background: Cerebral Venous Thrombosis (CVT), commonly known as Cerebral Venous Sinus Thrombosis (CVST), is a type of venous thrombosis that affects the dural venous sinuses and cerebral veins. It is a significant subtype of cerebrovascular disease and is a leading cause of stroke in young individuals in India. In fact, an autopsy series conducted in the late 1980s found that CVST accounted for nearly 10% of all strokes in India. Materials & Methods: This is hospital based cross sectional observational study which was conducted in the  Department of general medicine of Private medical college with study period of 1 year. The total sample size of the study was 25 patients. The collected data was entered in Microsoft Excel. Coding of the variables was done. Analysis was done using SPSS software (Version 27, IBM). Results: Among the 25 patients, 9 males and 16 females were part of the study. Age distribution: 30 and 80 years groups each had one person (4% and 8% respectively). 31-40 years group had three individuals (12%), 41-50 years had six (24%), 51-60 years had seven (28%), and over 60 years had eight (32%). Co-morbidities affected 84%, with motor weakness in 76%, sensory deficit in 64%, seizures in 60%, lateral rectus restriction in 36%, and aphasia in 44%. Papilledema was in 24%, coma in 8%. Anaemia and hypertension affected 95% each. Diabetes mellitus affected 85%, infections 69%, autoimmune associations 37%, and malignancy 20%.Conclusion: CVT is a disease with various symptoms and clinical features, including stroke in young individuals. It is treatable and has a positive prognosis with improved imaging techniques. Alcohol consumption is a significant risk factor. The study aimed to provide information on risk factors and clinical manifestations. Further research is needed to better understand this condition.