Comprehensive Analysis of Risk Factors, Diagnosis, and Management Strategies for Diabetic Peripheral Neuropathy in Asian Population

Abstract

Diabetes, particularly prevalent in rice-dependent regions of Asia, is experiencing an alarming rise. This study investigates the concerning trend of Diabetic Peripheral Neuropathy (DPN), a complication increasingly diagnosed at the time of diabetes detection. We aim to identify both modifiable like HbA1c, smoking, BMI and non-modifiable such as age, diabetes duration risk factors associated with this nerve damage. Additionally, we explore diagnostic methods like skin biopsies and nerve conduction studies for confirming DPN. This review also describes the effectiveness of various treatments in managing DPN symptoms. These include glucose control, pain management medications, lifestyle modifications, blood pressure control, and cholesterol management. The findings highlight the importance of early risk factor management to prevent complications. Furthermore, the study emphasizes the need for a comprehensive treatment approach combining both pharmacological and non-pharmacological interventions to improve the quality of life for patients with diabetic peripheral neuropathy.