Elastic Liposome Gel Scheme for Delivery of Polymixin Bacterium Sulphate in Deep Skin Infection

Abstract

Prehospital treatment that is provided on-site is essential for reducing the severity of injuries resulting from acute Skin infection, particularly those that are second and third degree. Skin infection usually cover a substantial portion of the body and have uneven forms and depths. It's always appropriate to use typical sheet-like wound dressings because of the severity and intricacy of infection injuries. As an alternative, large-scale, rapid, and convenient dressing changes can be achieved with sprayable dressings. Depending on the reagent composition, they can also stop secondary damage and infection. In addition to acting as a therapeutic barrier to relieve pain and provide moisturization, sprayable skin infection dressings also absorb extrudates, guard against bacterial infections, and transport tiny molecules and medications. The latest advancements in sprayable hydrogel-based wound dressings are covered in this study. A summary of the many types of burn wounds, the best burn dressing designs and attributes, and the state of commercial spray-on burn dressings are provided. Researchers are actively concentrating on altering the solution viscosities, propellant systems, and pump nozzle designs for spray formulations in order to attain the best healing capabilities employing sprayable wound dressings. Lastly, the topic of replacing skin transplant procedures with hydrogel-based dressings for tissue regeneration is covered.