Hs Crp As a Prognostic Factor in Acute Myocardial Infarction.

Abstract

Background: Acute myocardial infarction (AMI) remains a significant public health issue in both industrialized and developing nations, such as India, despite the advancements made in diagnosis and management over the past thirty years. the current investigation was undertaken to understand the Association between Elevated Levels of hs-CRP and its Risks During and After Acute Myocardial Infarction. The primary objective was to determine the relationship between hs-CRP levels and the likelihood of developing recurrent acute coronary syndrome, new-onset atrial fibrillation, ventricular tachycardia, heart failure, decompensation, and mortality. Materials & Methods: This is hospital based cross sectional observational study which was conducted in the  Department of general medicine of Private medical college with study period of 6 months. The total sample size of the study was 50 patients. The collected data was entered in Microsoft Excel. Coding of the variables was done. Analysis was done using SPSS software (Version 27, IBM). Results: Of the 50 patients, 41 (82%) were males and 8 (18%) were females. Maximum patients (35%) were aged between 41 and 50 years followed by 61-70 years (30%), 51-60 years (25%) and 31-40 years (10%). The youngest patients had 34 years of age and oldest was 70 years. 30% are hypertensive, and 34% have diabetes mellitus. Most of the patients (95%) had symptoms of chest pain. the types of AMI 49% had extensive anterior wall, 30% had inferior, 12% had anteroseptal and 9% had anterolateral. Hs – crp and  ESR was found to be 90% and 64% respectively high among the study patients. Conclusion: Elevated hs-CRP levels in AMI patients indicate inflammation's role in MI development, with prognostic significance; high levels upon admission are linked to poor outcomes, suggesting increased complication risk during hospitalization. Keywords: Hs CRP, Prognostic factor, Acute myocardial infarction