Pharmaceutical Standardization of Rajata Bhasma (Incinerated Silver Ash) Prepared with Two Methods by Using Classical Heating and Muffle Furnace

Abstract

Introduction: Pharmaceutical preparation of Rajata Bhasma (incinerated processed Silver) with two methods by using classical heating and muffle furnace is an original research work based on Rasa Shastra (Indian Science of Alchemy, Metallurgy and Iatrochemistry) to determine the differences in preparation along with observation of various changes occurring during both processes, time taken and temperature required. The completion of both processes is evaluated by classical Bhasma (Ash) assessment parameters. The importance of this work was determined on the premise of increasing popularity of nanoparticle of Silver in therapeutic usage and a need for alternative methods of preparation for the same.

Objectives: Comparative understanding of preparation of Rajata Bhasma using classical heating techniques (Puta) as well as the use of Muffle furnace with standardized temperature range using both Hartala Marita Rajata Bhasma (purified Arsenic trioxide processed Silver Ash) and Kajjali Marita Rajata Bhasma (Black mercuric sulphide processed Silver Ash).

Methods: Hartala Marita Rajata Bhasma (purified Arsenic trioxide processed Silver Ash) and Kajjali Marita Rajata Bhasma (Black mercuric sulphide processed Silver Ash) were prepared by adopting different purificatory process explained in Ayurved Rasashastra.

Results: Modified heating pattern (Preparation of ash in Muffle furnace) has reduced number of repetition of heating. The maximum temperature was around 600⁰C.

Conclusions: The method of preparation of Rajata Bhasma using Kenduka yantra and Muffle Furnace required 14 puta and therefore, can help with reducing the time and fuel consumption in comparison to the classical method which required 17 puta.