Effectiveness of a Novel Antimicrobial Dressing in Treating Chronic Venous Leg Ulcers

Abstract

Aim and objective: The purpose of this study was to investigate the effectiveness ofSilver containing wound dressing in Leg ulcer patients with chronic venous disease. Methods: 60 patients with venous leg ulcers were treated with silver colloid dressings for four weeks, followed by conventional dressings for four weeks with or without having signs ofinfection were treated. Clinical evolution of the wound in terms of size, depth and ulcer painwere monitored for eight weeks. In this study, two participants defaulted and lost to follow up. Results: The wound condition has significantly improved after 8 weeks with completely healed ulcers in 4 patients, 48 (76%) patients had improvement and 2 patients had deteriorated wound requiring debridement. An average of 54% reduction in size and 60% reduction in depth of ulcers seen. No adverse events were encountered related to wound dressings. Participants reported less pain on pain scores as the study progressed. Conclusion:  According to this study, silver wound dressings have an acceptable efficacy for treating chronic venous leg ulcers where biofilm formation might inhibit healing.