Exploring Phytoconstituents as Potential Therapeutics for Poly Cystic Ovarian Syndrome: A Comprehensive Review

Abstract

Poly Cystic Ovarian Syndrome (PCOS) is a complex and prevalent endocrine disorder affecting women of reproductive age. This comprehensive review explores the potential of phytoconstituents as therapeutics for PCOS. PCOS is characterized by hormonal imbalances, metabolic disturbances, and reproductive abnormalities. Current treatment options are associated with limitations and side effects, necessitating the exploration of alternative therapeutic approaches. Phytoconstituents, derived from plants, offer a diverse range of bioactive compounds with the potential to address multiple facets of PCOS pathophysiology. This review synthesizes existing research on phytoconstituents such as curcumin, resveratrol, and berberine, highlighting their efficacy in mitigating insulin resistance, modulating hormonal imbalances, and improving reproductive outcomes. The review discusses preclinical and clinical studies, providing insights into the regulatory aspects of these phytoconstituents. The findings suggest that phytoconstituents present a promising avenue for the development of novel therapeutic interventions for PCOS, offering a potential solution with fewer adverse effects. However, further research is warranted to elucidate the mechanisms of action and ensure the safety and efficacy of phytoconstituents in the management of PCOS.