A Study on Relationship between Type-II Diabetes Mellitus and BMI among Patients with Non-alcoholic Fatty Liver Disease

Abstract

Introduction: Diabetes and its complications are a major public health concern among all age groups. Indians are highly susceptible to diabetes with modest over weight, central obesity, and decrease in physical activity. Obesity is the leading factor in the pathogenesis of health disorders such as hypertension and type-2 diabetes mellitus. However, there is little data available on diabetes and its correlation with BMI among Indian population. Objective: This study was aimed to determine the effects of elevated body mass index (BMI) on type 2 diabetes mellitus (DM) onset and its complications among subjects. Methodology: Total 200 subjects of all age groups with or without T2DM were included who had non-alcoholic fatty liver disease. Data on demographic profile and treatment history of diabetes were collected using pre-designed questionnaire. FBS and HbA1c were tested. Weight and height were measured to calculate BMI. SPSS was used to assess the relationship between T2DM and BMI. Results: The overall prevalence of diabetes was 93% (male: 49%, female: 51%).Prevalence of diabetes increased as the BMI of participants increased. Prevalence of diabetes among obese individuals (BMI ≥25 kg/m²) was 57% compared to 0% among normal weight individuals. Obesity was associated with higher risk of diabetes compared with the individuals of control group as well as with normal weight in this study. Conclusion: Having even moderately elevated BMI is associated with increased risk of developing DM complications. BMI and FBG are positively correlated and subjects are therefore at risk of obesity and its related conditions.