Synthesis and Biological Activity of a New Schiff Base Ligand Pyridazine Based

Abstract

In this work , -bis ( -[ -sulfanyl-ethylimino)-methyl]- -( -nitro-phenylazo)- -metoxy-phenol)pyridazine ( ) was prepared and its antibacterial properties have studied. The structures of all the newly synthesizedcompounds have been comfirmed by elemental analysis, IR, H-NMR. Anti bacterial effects of compounds ( and )have been studied. Following concentrations of materials were used: a= g/ml and b= M. Study was done ontwo strains of S.aureus and E.coli that experiments were done in Trypticase Soy Broth (TSB) and Nutrien Agar (TSB;Difco Laboratory). It is likely that these synthetic materials exert higher antibacterial effect on gram positive bacteriain comparison with gram negative.