A Review of Carbapenem-Resistant Acinetobacter Baumannii as A Biofilm Producer Pathogen

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Wan Alif Syazwani Wan Alias, Habsah Hasan, Nik Rozainah Nik Abdul Ghani, Siti Asma’ Hassan, Norzila Ismail

Abstract

Acinetobacter baumannii (A. baumannii) has become a major hospital-acquired infectious agent and is rapidly developing resistance to antimicrobials that are routinely prescribed. Carbapenem-resistant A. baumannii (CRAB) was one of the strains that had been resist to carbapenem. The CRAB has ability in biofilm formation that can lead to severe nosocomial infection. It gained popularity recently for being associated with devastating soft tissue infections in humans mostly in healthcare workers and patients admitted in ICUs. The amount of data currently available provides support to the theory that rising infection rates are caused by the widespread contamination of progressively resistant A. baumannii in hospitals.

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