Risk Factor Analysis of Latent Tuberculosis Infection in Mamuju Tengah Regency
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Abstract
Introduction: Infectious latent TB (ILTB) has been recognized as one of the greatest barriers to achieving the goals of the End TB Strategy. The burden of Infectious Latent Tuberculosis (ILTB) in the world in 2019 is estimated at 1.7 billion people of which 35% are from the Southeast Asia region including Indonesia. Data from the West Sulawesi Provincial Health Office reported an estimated 7,241 cases of Latent TB Infection. Mamuju Tengah district is an area that contributes to the incidence of TB, which is 164 per 100,000 population. The data shows that the risk of TB Latent Infection is estimated at 682 people, but out of a total of 125 TB Latent Infection target screenings, there were 43 positive cases using the Tuberculin test.
Objectives: This study aims to determine the risk factors for the incidence of Latent TB Infection in Central Mamuju Regency.
Methods. This research is a quantitative study with an analytical survey approach, with a Case Control Study design. The sampling technique used exhaustive ampling using the Lemeshow formula (1990).
Results: The results were analyzed using the chi-square test and logistic regression test.The results of the study on the variables of DM disease status (OR = 6.428 with 95% CI = 2.124-20.627), nutritional status / IMT (OR = 1.802, with 95% CI = 0.739-4.339) BCG Vaccine History (OR = 6.637 with 95% CI = 2.633-17.037), house occupancy density (OR = 5.660 with 95% CI = 12.252-14.309) and house ventilation (OR = 5.052 with 95% CI = 2.048-12.566). The results of logistic regression analysis showed that the history of BCG vaccine administration was the main risk factor for the incidence of latent TB infection in Mamuju Tengah district.
Conclusions: Risk factors for latent TB infection were DM status, BCG vaccine history, house density and house ventilation. Increased logistical availability of Tuberculin testing in risk groups needs to be widespread to reach more Latent TB cases in Mamuju Tengah District.