“Phytochemical Investigation And Hypoglycemic Evaluation Of Artemisia Indica Willd Medicinal Plant”

Abstract

In this study, the herb Artemisia indica, which has been utilized for therapeutic purposes for centuries, is investigated to see whether or not it possesses any potential anti-diabetic properties. Based on the findings of research that evaluated acute toxicity, Research has demonstrated that a terpenoids, alkaloids, and flavonoid-rich hydroalcoholic extract of Artemisia indica leaves is a safe food option   It was discovered through experiments conducted on rats that had developed diabetes as a result of streptozotocin that the extract possesses powerful anti-diabetic capabilities. A comparison was made between the treatment groups and the control group, which consisted of people who had diabetes. Dental glucose tolerance, insulin serum levels, and fasting blood glucose levels were all significantly improved in the treatment groups. According to the results of the histological analysis, the pancreatic islets' structural integrity had been maintained in addition to the finding that there was an increase in the expression of insulin in beta cells. Additionally, Throughout the trial, the extract not only displayed a significant degree of antioxidant activity, but it significantly reduced oxidative stress indicators. Additional research into the molecular mechanisms and medicinal uses of Artemisia indica is urgently required because of the plant's potential to function as a natural anti-diabetic.