A Comprehensive Review: Exploring Conventional Medications and Ayurvedic Solutions for Managing Acne Vulnerabilities

Abstract

Over the preceding decades, there has been a discernible surge in the exploration of medicinal plants and phytochemicals as potential agents for the treatment of skin ailments, with a particular focus on addressing the challenges posed by acne vulgaris. Acne vulgaris, characterized as a persistent immune-mediated ailment of the pilosebaceous unit, predominantly manifests itself in teenagers and young adults, presenting a considerable burden on affected individuals. The therapeutic approach to acne vulgaris centers around mitigating the four primary components that contribute to its pathogenesis: increased sebum production, hyperkeratinization, proliferation of Cutibacterium acnes, and the presence of inflammation. Conventional treatments for acne vulgaris include the application of topical retinoids, benzoyl peroxide, antibiotics, and, in more severe cases, oral isotretinoin. However, the landscape of acne treatment is evolving, with a growing recognition of the potential benefits of herbal medicine as a supplementary and alternative therapeutic avenue. This emerging paradigm acknowledges the holistic and synergistic properties inherent in medicinal herbs and phytochemicals, providing a nuanced and potentially more sustainable approach to managing acne vulgaris. Against this backdrop, the primary objective of the present study is to delve into the efficacy and safety profiles of medicinal herbs and phytochemicals in the treatment of acne vulgaris. By examining the intricate interplay between these natural compounds and the underlying pathogenic mechanisms of acne, this research seeks to contribute valuable insights into the evolving landscape of dermatological therapeutics, paving the way for a more diversified and personalized approach to acne management.