Review of Breast Cancer Prognosis: MicroRNAs/lncRNAs, Obesity, The LPR6 Biomarker, and Night Fasting

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Dewi Rostianingsih, Melly Kristanti, Ratna Puspita, Novita Verayanti Manalu, Steven Arianto, Ketut Lisnawati, Jelita Siska Herlina Hinonaung

Abstract

Introduction: Prognosis is an important determining aspect in decision-making regarding the course of treatment needed and follow-up of breast cancer patients. The prognosis of breast cancer is challenging because of the heterogeneity of the disease. The growth of breast cancer is an infection that affects the world's well-being. Although Breast Cancer Growth Therapy continues to improve, survival in patients remains unacceptable because there is no direct evidence that can predict the course of the disease and the extent of Breast Cancer chemoresistance. As a result, specialists must strictly differentiate them in order to develop endurance further.


Objectives: This paper attempts to describe the prognosis of breast cancer from aspects related to hormones, namely LPR6 and microRNAs/IncRNAs biomarkers, as well as from aspects related to lifestyle, namely obesity and night fasting.


Methods: This writing audit review plans to outline four aspects of breast cancer prognosis. This study uses a literature review approach. This review summarizes the work in progress on image screening for Breast Cancer Guessing and includes articles from 2006 to 2021.


Results: The investigation of the articles found that LPR6 has an adverse influence on the growth of tumor invasion and thus may be an essential biomarker in breast cancer prognosis; Subtype characterization and breast cancer prognosis can be investigated by looking at microRNAs and IncRNAs so that scRNA-seq-based methods can be a good choice; Obesity correlates directly with breast cancer prognosis, BMI level correlates with increased estrogen receptors having an independent effect on breast cancer survival; Night fasting can be a consideration related to the prognosis of breast cancer, that night fasting can reduce the amount of glucose so that night fasting makes HbA1c fixation lower.

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