DUREDAS Technology: A Cutting-Edge Bilayer tablet strategy

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Saurabh D. Nikam, Rahul Y. Pagar, Avinash B. Gangurde, Niketan N. Khairnar, Makrand V. Hire, Mayur K Joshi

Abstract

Introduction:


The dual drug delivery system, or DUREDAS, combines the liberate of one medicine, or two disparate drugs combined in one dosage form using a bilayer tablet technology. Two layers are used in this technology: immediate release, which releases the medication as a loading dosage, and persistent release, which extends the duration of the medication's effects. The simultaneous release of two distinct medications in two separate ways is an additional strategy that enables them to function as individualized medicine for patients with various problems or in conjunction with one another to treat the same medical condition. A compressed granule with instant release and a granule with regulated release are applied to the tablet to create a bilayer effect. The gastrointestinal tract (GIT) absorbs liquid, which the regulated hydrophilic matrix system then expands to dissolve. In this review Dual drug delivery system (DUREDAS) technology of formulating bilayer tablets with different approaches and benefits is elaborated.


 Objectives: The objective of this review is to comprehensively evaluate and analyse DUREDAS    Technology, focusing specifically on its cutting-edge Bilayer tablet strategy. This review aims to provide an in-depth understanding of the technology's key features, capabilities, and potential impact in the pharmaceutical and healthcare industries. The objective is to elucidate the advantages, challenges, and overall effectiveness of this approach.


Conclusions:


Dual drug delivery systems (DUREDAS) are a state-of-the-art method in pharmaceutical research, with several benefits that have the potential to change the face of medicine. In the pursuit of more individualized and efficient therapeutic approaches, researchers will continue to focus on these systems' capacity to handle the intricacies of different diseases and enhance patient outcomes.

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