The New Therapeutic Studies for Irreversible Optic Nerve Damages

Abstract

The irreversible optic nerve damages are known as optic neuropathies result in permanent loss of vision. The optic neuropathy usually affects the anterior optic nerve, leading to death of retinal ganglion cells (RGCs) and axonal loss. At present, there is no effective treatment to recover degenerated or damaged optic nerves because of their inability to regenerate themselves. The present essay has adopted a literature-based methodological approach to discuss epidemiological, pathophysiological, and clinical profile of the various optic neuropathies. The article traces the prevalence of optic neuropathies in Turkey and discusses the causes and effects of irreversible optic damage. Moreover, it reports on main rodent models used in the research conducted on optic neuropathy. In addition, the paper examined the current treatments used for the management of patients suffering from irreversible optic nerve damage and suggests options for future approach on introducing new treatments in the field. Thus, the dissertation holds significant implications as it helps advance the existing understanding regarding epidemiology, pathophysiology, and clinical types of optic neuropathies. Furthermore, it helps highlight the potential for new approaches in exploring treatments for irreversible optic nerve damage, which can guide future researchers in the area of activity.