Antidiabetic Effect of Ethanolic Extract of Caesalpinia Bonduc Seeds in Streptozotocin-Induced Diabetic Rats

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Hemant V. Deore, Shaikh Muzaffar, Pravin Gomase, Rahil Khan, Touseef Begum, Ravindra R. Patil, V.L. Badgujar,T.J. Shaikh, Irfan Ahmad, Syed Umar Faruq, Siddiqui Nameera, Shaikh Saniya, Shahid F.Pathan, Qazi Wasil, Nawaz Sharif, Ansari Yaasir Ahmed


Purpose: A study of historical literature reveals that diabetes was widely recognized and understood in India. Herbal medicines have long been used to treat a range of diseases. Nature has provided an extensive number of medicinal plants that are useful to all living things. While the fundamental merits of many plants have long been recognized, many others remain to be fully researched. Therefore, it is necessary to look into their uses and conduct pharmacognostic and pharmacological research in order to determine their therapeutic characteristics. Actually, diabetes is becoming a global problem. Thus, the purpose of this research is to open up new avenues for improving the medicinal uses of Caesalpinia bonduc for the specific ailment of diabetes. Method: The goal of the current study is to assess the anti-diabetic effects of Caesalpinia bonduc seeds against STZ-induced diabetics. Result: The body weight and blood glucose level of the seed extract of Caesalpinia bonduc was found to be significantly lower and comparable to that of a standard anti-diabetic medicine (Metformin). Conclusion: In the current study, albino wistar rats were used as test subjects to evaluate the anti-diabetic activities of a methanolic seeds extract of Caesalpinia bonduc.

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