Benefits of Crude Antimicrobial Delivery of Pharmaceutical: A Traditional Yet Upcoming Era

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Karabi Kalita, Prachi Mall, Deepika Raina

Abstract

Almost 90% of the population suffers from skin diseases, including atopic dermatitis, which is caused by S. aureus. Because synthetic skin infection treatments are expensive and have a number of side effects, drugs produced from natural sources can be used. These drugs are widely available, inexpensive, safe, and effective, with minimal side effects. Saponins, alkaloids, tannins, flavonoids, and steroids were among the phytochemical components found in the herbs investigated. Alkaloids have antibacterial properties due to their ability to inter-chelate with the DNA of Gram positive and negative bacteria and interfere with cell division. Kaempferol, chlorogenic acid, and kaempferol-3-O-D-glucoside are active bio-components of oleander flower extracts with potent anti-inflammatory properties. Synthetic magnetite nanoparticles or an aqueous extract of Calotropis procera inhibit Gram-positive bacteria. Antimicrobial chemicals identified in MpEO, Lawsonia inermis, IL-6, Tagetes erecta, and other plants can be used in topical drug delivery methods as formulations.

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