The study of association between Depth of Invasion, Tumor Budding, and Worst Pattern of Invasion with Tumor stage and Lymph node status in Oral Squamous cell carcinoma

Abstract

Malignancy of oral cavity is a major health burden in India, which contributes to 1/3^rd of the global oral cancers. Annual incidence of oral cavity cancers is 77,000 and death due to these cancers is estimated to be 52,000 per year. Among them, 84-97% of oral cancers are histologically diagnosed as Squamous cell carcinomas, thus accounting to be the most common histologic type. ⁽¹⁾