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Hospital-acquired pneumonia is associated with greater rates of morbidity and mortality, which need to be identified and treat immediately and completely. We describe a case of a 70 years old female pneumonia patient, who arrived with abdominal pain and shortness of breath. She later developed mild hyponatremia and was at risk for developing syndrome of inappropriate antidiuretic hormone secretion. Stenotrophomonas maltophilia, a Gram-negative bacillus generally cause opportunistic infections in immunocompromised or critically ill individuals, was identified as the causal organism found in patient's blood culture. The patient was treated gently by antibacterial therapy. The patient was discharged with instructions after demonstrating improvement in her health and symptoms. The necessity of identifying and treating pneumonia, hyponatremia, and syndrome of inappropriate antidiuretic hormone secretion in this patient is demonstrated by this case. It also draws attention to the difficulties and disagreements surrounding the diagnosis and management of this infection.