Isoflavone Supplementation Alleviates Vascular Hardness in Women in the Perimenopausal to Postmenopausal Stages: A Systematic Study

Abstract

Isoflavones, derived from plants with estrogenic and antioxidant properties, offer

potential benefits for women during menopause. With menopause encompassing a

significant period of a woman's life, addressing its discomfort as routine can be misguided.

While  Menopausal  Hormone  Therapy  [MHT]  effectively  manages  menopausal

symptoms, its use is linked to heightened risks of coronary heart disease, breast cancer,

and vascular events. In cases where MHT isn't viable, isoflavones serve as a viable

alternative. This study investigates the potential of isoflavone supplementation in

alleviating menopausal vascular stiffness in perimenopausal and postmenopausal women,

emphasizing the modulation of ovarian hormones and associated parameters. The study

reveals that isoflavones effectively mitigate the prevalent symptoms of vascular stiffness

in perimenopausal to postmenopausal women, offering stability across several key

parameters defining vascular hardness. In conclusion, isoflavones show promise in

alleviating vascular stiffness symptoms among women in their perimenopausal to

postmenopausal stages.