Green Preparation and Characterization of Silver Nanoparticles from Aloe Vera and Neem Leaf Extracts and Studying their Antimicrobial Activity against Oral Pathogens

Abstract

The use of toxic compounds in conventional nanoparticle production processes can cause environmental damage. Green synthesis will therefore be a necessary process to minimize the production of these compounds. Previous studies have shown that silver nanoparticles have potent antibacterial properties. Silver was used to create a nanoparticle because it induces cell wall breaking due to intracellular material leakage, which makes it an efficient antibacterial agent. Aim : Aim of the study was to test the antimicrobial properties of silver nanoparticles mixed with aloe and neem leaf extracts against oral pathogens. Material and methods: Antibacterial activity of the corresponding nanoparticles against the strains of Enterococcus faecalis, Streptococcus mutans and Candida albicans. For this experiment, MHA agar was used to identify the zone of inhibition. The zone of inhibition was tested after the incubation period. Result : With increasing concentrations, increased values are seen for all three bacteria. Conclusion: Within the limits of the study it can be concluded that silver nanoparticles have good antimicrobial properties and further can be incorporated in dentistry either as the drug delivery systems or can be used to coating materials to improve their properties.