Evaluation of Intelligence of Edentulous Patients and its Correlation with their Quality and Quantity of Saliva- Invivo Study

Abstract

Saliva plays a crucial role in maintaining oral homeostasis and significantly influences prosthodontic outcomes, particularly in edentulous patients. This study aimed to evaluate the association between intelligence quotient (IQ) and the qualitative and quantitative properties of saliva. A total of 40 participants aged 16–84 years, including 25 partially edentulous and 15 completely edentulous individuals, were assessed. IQ was measured using the Wechsler Adult Intelligence Scale–IV (WAIS-IV), and Full-Scale Intelligence Quotient (FSIQ) scores were derived through standardized procedures. Unstimulated saliva samples were collected using the passive drool method and analyzed for parameters including pH, amylase, catalase, protein concentration, viscosity, and salivary quantity. Pear  son correlation analysis was employed to determine the relationship between IQ and salivary characteristics. The results demonstrated weak but notable correlations between IQ and salivary parameters. Higher IQ levels were associated with increased salivary pH and amylase activity, along with reduced catalase levels, protein content, viscosity, and salivary quantity. Additionally, variations in salivary characteristics were found to influence oral function and prosthesis performance in edentulous individuals. These findings suggest a potential neurophysiological link between cognitive function and salivary regulation. Within the limitations of the study, the observed associations highlight the importance of considering salivary characteristics during prosthodontic treatment planning. Tailoring clinical approaches based on individual salivary profiles may enhance denture retention, stability, patient comfort, and overall treatment outcomes.