Association of Serum Adiponectin and Leptin with Blood Pressure and Dyslipidemia in Preeclampsia

Abstract

Introduction: To assess serum adiponectin and leptin in preeclampsia then controls and evaluate the potential of adiponectin and leptin as a diagnostic and prognostic marker for preeclampsia.

Objectives: To assess serum adiponectin and leptin in preeclampsia then controls and evaluate the potential of adiponectin and leptin as a diagnostic and prognostic marker for preeclampsia.

Methods: This cross-sectional study included 100 preeclamptic pregnant women and 50 controls. The serum adiponectin and leptin concentrations were determined through the enzyme-linked immunosorbent assay method. Additionally, sociodemographic, and laboratory parameters were assessed.  

Results: Mean serum adiponectin and leptin levels were significantly higher in the preeclampsia group compared to the control group. These levels were significantly positive correlation with blood sugars, BMI and dyslipidemia (P=0.001**).

Conclusions: Serum adiponectin and leptin levels are significantly elevated in preeclamptic pregnancies, supporting its potential as a diagnostic biomarker.