Syntshesis, Characterisation and anti-bacterial activities of 2-Thiouracil Derivatives

Abstract

This study presents the synthesis and comprehensive characterisation of fresh organic compounds. The synthesized compounds were obtained as white solid crystals, each displaying distinct melting-points, thereby reflecting their identical molecular architectures and thermodynamic stability. Structural elucidation was performed using a combination of complementary analytical techniques. Fourier-transform infrared (FT-IR) spectroscopy enabled the identification of characteristic functional groups. Proton (1H) and Carbon-13 (13C) Nuclear Magnetic Resonance (NMR) spectroscopy provided detailed insights into the molecular framework, while high-resolution mass spectrometry (HRMS) confirmed the molecular masses and offered fragmentation patterns consistent with the proposed structures. The integrated use of these techniques ensured reliable structural validation and highlighted the distinctive features of the synthesised compounds. The findings underscore the significance of systematic characterization in advancing the understanding of organic molecules and lay the foundation for their prospective applications in industrial processes and synthetic chemistry.