Chemical Analysis of Hemigraphis Colorata Methanol Extract and Its Efficacy Against Human Clinical Pathogens

Abstract

Introduction: The potential pharmcological values of curing many are high in the traditional herbal plants. Hemigraphis colorata is one of the perennial tropical herbs that is used mostly. to achieve aestheticism and new antibacterial treatment.

Objectives: The chemical research analyses composition and biological properties of Hemighraphis coloratoto methanol extract. Illustrate its possible use as an antibacterial extract. The methanolic extract was assessed on its possible use as an antibacterial extract. antibacterial action to several bacterial strains. The extract has a maximal inhibitory. zone of S. mutans 21mm, P. aeruginosa 20 mm, V. cholerae 20 mm, S. aureus 21mm at a. concentration of 100 ug/ml. Additional MIC values of 60,60, 60, 80,80,100 and100ug/ml and. S. typhi has a value of 40,40, 60,60, 80,80, 100,100 ug/ml on MBC. This was determined as E. coli, S. Paratyphi, Aeruginosa, and V. parahaemolyticus respectively.

Results: The extract showed great antibacterial effect towards some humanoid medical pathogens. There was a presence of bioactive chemicals and therefore, deep research was conducted with the help of such procedures include gas GC-MS, FTIR, and phytochemical screening. It also exhibited high free radical-neutralizing properties which are confirmed from testing antioxidant assay.

Conclusion: These results explicate H. colorata's therapeutic potential as a naturally occurring source of bioactive chemicals, underscoring its potential for use in medical research and pharmaceutical development.