Effect of Photodynamic Therapy with Verteporfin in Patients with Choroidal Neovascularisation Caused by Age Related Macular Degeneration- A Prospective Study

Abstract

Aim: To see the Effect of Photodynamic therapy with verteporfin in patients with choroidal neovascularisation caused by age related macular degeneration

Materials and methods: The Study was prospective. 118 patients diagnosed with CNV secondary to AMD between February 2017 to March 2019, were including, study conducted in the department of ophthalmology in Shri Aurobindo Medical Research Centre Raipur Chhattisgarh, India.

Results: In current study, there was significant difference between the two group. Regarding to Height Group A mean 4.87 SD 1.65) and group B mean 5.463 SD .3931 are significant, mean (SD) of right intraocular pressure measured mean.30 SD .460 mmHg (10 mmHg– 32 mmHg) in the group A and mean 0.43 SD 0.499 mmHg (10 mmHg–28 mmHg) in the group B significant at p<0.05 level; and Hypertension- Group A 0.42 SD 0.497, and Group B mean 0.61 SD 0.497 are significant at <0.05 level.

Conclusion: ARMD patients had a mean age of 55.36 years most commonly affected. Females were found to have a higher prevalence of ARMD in our study. The 1-year result of Photodynamic Therapy (PDT) for AMD patients with predominantly classic and pure occult Choroidal Neovascularization (CNV) in eyes seems to be better than that of Photodynamic Therapy (PT) and Verteporfin in Photodynamic Therapy (VPT) studies.