Phytochemical Investigation and Cytotoxic Activity of Methanolic Extract of Eleusine Coracana

Abstract

In this study, phytochemical investigation and cytotoxic activity of methanolic extracts of Eleusine coracana were performed. Three compounds, stigmasterol, beta-sitosterol and lupeol were isolated from the methanolic extract of Eleusine coracana. These compounds were isolated for the first time from this millet. Methanolic extract of Eleusine coracana was evaluated for the cytotoxic activity at various concentrations against HepG2 liver cancer cells in vitro. The extract showed cytotoxic activity at 250µg/mL. The results of the present proved that Eleusine coracana is active against the cancer due the presence of the active phytochemicals with anticancer properties.