Formulation and Characterization of Herbal Antifungal and Anti- Inflammatory Foot Repair Serum

Abstract

Background: Dry and cracked feet are a result of inadequate moisturizing, increased exposure to pollutants, as well as certain medical conditions like psoriasis, thyroid, diabetes, and eczema so to prepared the highly concentrated foot repair serum.Due to the absence of any oil glands, the feet skin has an ability to crack and dry out. Serum has a thinner viscosity; they not only absorb fast but also reach the deepest layers of the skin to target different parts and provide optimum efficacy. Because of their potent effects and very few adverse effects compared to those of synthetic medications, herbal formulations have consistently attracted significant attention.

Result: The extract of Dimocarpus longan duch and Fragaria × Ananassa were used for the formation of herbal antifungal and anti-inflammatory foot repair serum by using solvent evaporation method and maceration method respectively. The optimization extract were characterised by UV/VIS Spectrophotometer, FTIR Spectrum measurement, HPLC measurement. The required quantity of ingredients like Carbopol 940 (used as a gelling agent), Triethanolamine (used as a pH adjustment), Propylene glycol (used as a humectant), methyl paraben and propyl paraben (used as a preservatives), ascorbic acid ( used as a antioxidant) were used for preparation of serum. Various evaluation parameters like Organoleptic testing, pH measurement, Stability study, Spreadability study, Viscosity measurement, Homogeneity. Therefore, present study the main aims to formulate and characterization of herbal antifungal and anti-inflammatory serum for the treatment of cracked heels.

Conclusion: The herbal antifungal and anti-inflammatory foot repaired serum was effectively produced and evaluated using a variety of official parameters, including spreadability testing, pH analysis, and viscosity measurement. Based on all of the investigated herbal serum formulations, M1, M2, and M3 each shown a substantially different rise in skin moisture (p<0.05).