In Vitro Antimicrobial Antibiofilm Efficacy of Econanosilver Against Uropathogenic Bacteria

Abstract

In recent times, nanoparticles are widely used for combating antibiotic resistance in urinary tract infections (UTIs). Here we have discussed various metal oxide and other nanoparticles and their different formation techniques including organic, nanodiamonds, chemical and green-synthesized inorganic, and composite materials. We have also compared there in vivo and in vitro effects against UTI in both male and females. The study also discusses the antibiofilm property of Costus igneus plant extract made in AgNPs against UTI enterococcal isolates. Biofilm formation property of bacteria makes them drug resistant and making UTI difficult to treat. Costus igneus AgNPs, having an average size of 65-150nm, showed potent antibacterial activity which also reduces biofilm formation by 81% as compared to other controls. 37.64, 725.7, and 61.08 μg/ml were the results of antimicrobial activity of MIC. Green synthesis of NPs is contributing to a safe and green environment reducing the toxic release