Study of Demographic Profile and Histological Characteristics in Patients of Biopsy Proven Iga Nephropathy

Abstract

Background: IgA nephropathy is the most common primary glomerulonephritis worldwide, accounting for 20 to 40 percent of patients with primary glomerulonephritis who undergo biopsy. Present study was aimed to study of histological characteristics & clinical outcome in patients of biopsy proven IgA nephropathy.

Material and Methods: Present study was single-center, prospective, observational study, conducted in patients of age  > 12 years, with biopsy proven IgA Nephropathy.

Results: The median age of patients in this study was about 37years. Male and female patients were almost evenly distributed in this study. Microhematuria and proteinuria was seen in almost all the patients at the time of biopsy in this study. The most common histological finding in this study was Mesangial hypercellularity, seen in about 90% patients.

Conclusion: Microhematuria and proteinuria was noted almost all the patients. The most common histological finding in this study was Mesangial hypercellularity, seen in about 90% patients.