Assessment of Therapeutic Properties of Schiff Base Derived from Alloxan

Abstract

Biological effects of pyrimidine derivatives are widely known. It has been demonstrated that the pyrimidine derivative Alloxan has anti-tumour property. The afore said chemical used to develop diabetes in animals and is an effective beta-cell toxin which terminates cells by producing hydroxyl radicals. Alloxan kills pancreatic islet cells directly and selectively, it is commonly used in diabetes research.

A potential path toward the development of new materials with a wide range of applications is offered by organometallic complexes. A foundation for developing drugs that may be applied in a variety of settings is provided by the electrical changes that take place between metal-ligand complexes. Schiff base antibacterial properties in vitro motivate scientists to create novel anti-biofoulants. Ligand preparation is accomplished under mild conditions with reasonably good to high yield. The synthesized Alloxan phenyl alanine is characterized using UV IR, NMR and screened for their antibacterial properties.