Effects of Juglans regia and Prunus dulcis on amnesia model of Alzheimer's induced by Scopolamine in Albino rats

Abstract

Introduction: Over the last two decades, the pharmaceutical and pharmacological sciences have developed positively and at a very good rate. With continuous modifications and enhancement., the principles of the ancient Ayurvedic system of medicine are used nowadays in which better ideologies. The primary reason for this modification and enhancement is the development of the brain. understanding, knowledge, and different types of trial-and-error methods. in the field of neurological sciences, understanding cognitive properties and functionalities is one of the major studies and tasks which needs to be performed and require multiple things especially living organisms and as the targeted subject, and many types of instruments, models, and methodologies along with drugs and medical devices.

Objectives: The objective of present research work was to know more about cognitive enhancement, different types of apps and medicines used for cognitive enhancement, some reasons for cognitive impairment, and some major models and behaviour Oriel tests that are used for different types of cognitive studies

Methods:Along with this information, some more things also focused on getting proper information like which experimental animals are used for these types of in vivo studies, different properties, and functions of almonds and walnuts for comparative studies, and the Morris water maze test for checking up the level of cognitive enhancement. In the Morris water, maze test setup, the readers will get to know more about that specific test as it is specially designed for testing up the memory enhancement as well as cognitive enhancement along with spatial learning.

Results: The research work displayed the result as both the test components improves the cognition power and memory of the rats of both the sexes after a continuous administration of doses for a long period of time as compared to the controlled group. The rats were able to escape much faster as compared to the training session

Conclusions: The results from the current study exposed that the consumption of dry fruits like walnuts and almonds Does increase the level of cognition and memory enhancement in terms of control and coordination along with spatial learning. The presence of omega-3 fatty acids involve nuts, does provide strength to the brain in the hippocampus region and also reduces the oxidative stress.