Unraveling the Future of Nutrition in Periodontics: A Comprehensive Review of Nutrigenomics

Abstract

 Introduction

Nutrigenomics, the study of the interaction between nutrition and genetics, offers new insights into periodontal disease management. Periodontal diseases, influenced by genetic, environmental, and lifestyle factors, can benefit from understanding how dietary components affect gene expression, inflammation, and tissue integrity, paving the way for personalized treatment approaches.

      Methods:

A systematic literature search was conducted to identify relevant studies exploring the intersection of nutrition, genetics, and periodontal health. PubMed, Embase, and other databases were searched using predefined keywords related to periodontics, nutrigenomics, and dietary factors. Studies published between [ January 1, 2010 and December 31, 2023] were included, with a focus on human and animal studies investigating the impact of dietary components on periodontal inflammation, tissue integrity, and gene expression.

Results:

This review synthesizes current evidence on the relationship between nutrition, genetics, and periodontal diseases. It discusses the influence of dietary factors such as antioxidants, omega-3 fatty acids, and vitamin D on inflammatory pathways, oxidative stress, and tissue repair mechanisms in the context of periodontal health. Additionally, the review explores the role of genetic variations in modulating individual responses to dietary interventions and susceptibility to periodontal diseases.

Conclusion

Nutrigenomics reveals the significant impact of dietary components and genetic variations on periodontal health. Personalized nutrition strategies, tailored to individual genetic profiles, hold promise for improving periodontal treatment outcomes and advancing the management of periodontal diseases. Further research is essential.