Managing Coexisting Anemia and Hypothyroidism: A Case Report Highlighting Drug Interactions

Abstract

Introduction: Hypothyroidism arises from the diminished levels of thyroid hormone, exhibiting a diverse range of underlying causes and clinical presentations. If left untreated, hypothyroidism rise to heightened rates of morbidity and mortality . Globally, the foremost cause of this condition stems from dietary iodine deficiency. This case study investigates a 44-year-old woman who was hospitalised in the general medicine department presenting symptoms such as dizziness, tiredness, acid reflux, and headache which was eventually diagnosed as hypothyroidism and anaemia.

Objectives: The main aim is to assess the pharmacological interactions in the therapeutic management of hypothyroidism.

Methods: The methodology involves selecting a patient with hypothyroidism and anaemia, reviewing their medical history, performing necessary lab tests, and adjusting medication timing to minimize drug interactions. The patient receives personalized treatment, regular follow-ups, and counselling on medication adherence and lifestyle modifications to monitor progress and improve quality of life.

Results: The case study demonstrates the significance of diagnosing and treating hypothyroidism, especially in their showcasing the potential complexities and challenges in management. In this patient concomitant administration of pantoprazole and Levothyroxine in the morning has been shown to suppress intra gastric pH level which results in heartburn.

Conclusions: The prevalent interaction among the Proton Pump Inhibitor(PPI) was identified with levothyroxine on co-administration with incorrect  interval between the drugs. Rigorous screening recommendations, pharmacist interventions with extensive patient counselling strategies including lifestyle modifications and drug related guidelines provides comprehensive knowledge for improving the quality of life in  hypothyroid patients.