Antioxidant and Antimicrobial Potentials of Acanthus Ilicifolius and Excoeceria Agallocha Mangrove Plant Raw Leaf Extracts

Abstract

In this study biological activities of whole raw leaf extract of a mangrove plant named Acanthus ilicifolius and Excoeceria agallocha were investigated. The extraction was performed by using a soxhlet apparatus. Antimicrobial activity and antioxidant activity were determined in the raw leaf extracts of selected plants. Based on the research results  Excoeceria agallocha raw leaf (EARL) extract exhibited higher antibacterial activity against gram (-)ve bacterial species like Pseudomonas aeruginosa(ZOI 6mm) and Streptococcus pyogenes(ZOI 5.7mm) and antifungal activity with Candida albicans(ZOI 6.5mm). Inaddition EARL extract also showed higher antioxidant DPPH activity(IC₅₀-36.05µg mL-1 ) and less ABTS activity (IC₅₀-100.34 µg mL-1 ) compared to the extracts of A.ilicifolius with DPPH and ABTS  activities  (IC_50-72.05 µg mL-1)  and  (100.346µg mL-1 ) respectively.A.ilicifolius showed higher antibacterial activity against gram (-)ve bacteria Streptococcus pyogenes and also exhibited high antifungal activity. According to current research observations,  the E.agallocha leaf extract has an excellent antioxidant potentials for application as a bioactive compounds in pharmaceuticals. Moreover, the A.ilicifolius extract exhibited significant antibacterial and antifungal activities. This experimental results confirmed the efficiency of the extracts as natural antimicrobials and suggested the possibility of employing them in the utilization of drugs for the treatment of infectious diseases.