A Comparative Study to Evaluate the Cardiorespiratory Profile of Rheumatoid Arthritis Patients Versus Normal Healthy Volunteers in a Tertiary Care Hospital in WB

Abstract

Introduction: Rheumatoid arthritis (RA) is a common chronic systemic rheumatic disease affecting joints, tendons, bursae and internal organs including the cardiovascular and respiratory systems. Patients with RA often show more unfortunate cardiovascular risk profiles, with higher frequencies of the metabolic syndrome and smoking history compared with the general population.

Aim and Objective: To evaluate and compare the cardiorespiratory profile of rheumatoid arthritis patients versus normal healthy volunteers in a tertiary care Hospital in WB.

Material and Method: This observational cross sectional case control study was conducted in a time span of 1 year after taking institutional ethical clearance and Informed consent of the participants. The study participants include two groups. One group is control group and other group is case group Written informed consent was obtained from all participants.

Result: In this instance, the average DBP Changes after IHT in Pre-Intervantion patients (mean±sd) was 88.4000±3.1082. The control group's mean DBP Changes Following IHT in Pre-Intervantion patients were 78.8250±3.3481 (mean±sd.) A statistically significant distribution of mean DBP Changes following IHT in the preintervention group was observed (p ≤0.0001).

Conclusion: We find that, in comparison to the general population, patients with rheumatoid arthritis (RA) had an increased risk of cardiorespiratory profile and mortality. Consequently, cardiorespiratory risk factor management must be a keystone of RA treatment. Out of 160 persons in our study, the Control group's mean 6MWD (Male) and 6MWD (Female) were substantially greater than those of the C group. Although there was a modest difference in mean SBP between the Case and Control groups, the difference was not statistically significant.