Epidemiological Patterns of Cancer and the Human Development Index

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M.A. Vekilyan, V.F. Osipov, L.I. Gerasimova, A.V. Fomina, V.I. Pak, A.E. Larkina

Abstract

Introduction: The burden of oncological diseases remains one of the most pressing challenges in modern medicine. Prostate cancer ranks fourth in global cancer statistics and is the second most common malignancy among men worldwide. In the context of rising incidence rates, investigating the relationship between the level of human development and cancer epidemiology is becoming increasingly significant.


Objectives: The aim of this study was to investigate the relationship between the Human Development Index (HDI) and the epidemiological indicators of prostate cancer, as well as to identify factors contributing to disparities in incidence and mortality rates across countries with varying levels of socio-economic development.


Methods: This study is based on an analysis of scientific publications retrieved from international bibliographic databases (PubMed, Scopus, Web of Science, and eLibrary). The methodology includes a comprehensive analysis of data from large-scale population-based and biomedical studies. A standardized analysis of incidence rates was conducted, taking into account age-specific coefficients. Official statistical data from international organizations and the findings of epidemiological studies were utilized.


Results: The study revealed significant disparities in prostate cancer incidence rates between countries with different levels of human development. Regions with a very high HDI reported substantially higher numbers of cases. The leading modifiable risk factors identified include tobacco smoking, alcohol consumption, obesity, and unhealthy dietary patterns. It was found that approximately 40% of cancer cases could be prevented by eliminating these risk factors.


Conclusions: A direct correlation was established between the level of human development and prostate cancer incidence rates. The availability of screening programs and the quality of medical care significantly influence patient survival rates. It was found that countries with a very high HDI exhibit higher incidence rates; however, they also demonstrate better survival outcomes due to well-developed diagnostic and treatment systems. Limited access to healthcare services in countries with low HDI leads to late-stage diagnosis and poorer disease outcomes. This study underscores the need for the development of early detection programs and the improvement of access to oncological care in all countries, regardless of their development level.

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